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Please check the official study guide for the most up to date course information

Genomics, Transcriptomics and Proteomics

Semester 3

The course contents includes the following topics:

  • Genome organisation of prokaryotes and eukaryotes.
  • Mechanisms of genome stability, alteration and evolution, as well as Genomic recombination.
  • Techniques of nucleic acids analysis.
  • DNA markers technologies.
  • Identification of genes only recognisable by their impact in the phenotype: a) Map based cloning; b) Genome wide association studies (GWAS); c) Identification of regions of homozygosity (ROHs).
  • Genomic and expression libraries.
  • Genomic databases.
  • Next generation sequencing techniques.
  • Quantitative analysis of gene expression, from microarrays to RNAseq, real time PCR and Epigenetic modulation.
  • One genome multiple proteomes.
  • Resolution of complex protein mixes through chromatographic techniques and 2D gel electrophoresis.
  • Digestion techniques of proteins in peptides.
  • Quantitative proteomics: Isotope (ICT) and Fluorescence (DIGE) labelling.
  • Analysis of proteins by mass spectrometry.
  • Identification of post-translational modifications.
  • Protein arrays.

Final Competencies

1  Students are supposed to acquire theoretical knowledge and basic practical skills enabling them to feel more confident when joining modern companies involved in bio-production.

2  Ability to perform high-level modern scientific research in the field of Genomics, Transcriptomics and Proteomics.

3  Ability to initiate more advanced (e.g., Ph.D.) study programs that require relatively deep knowledge on the field of Genomics, Transcriptomics and Proteomics.

Further course information can be found here: